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产品简介
| 英文名称 | Anti-MOG Polyclonal Antibody |
| 别名 | MOG(35-55);myelin oligo-dendrocyte glycoprotein-MOG;MGC26137;MOG alpha 6;MOG;MOGIG2;Myelin oligodendrocyte glycoprotein; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:400-800. IHC-F 1:400-800. ICC 1:100-500. IF 1:100-500 |
| Gene ID | 4340 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q61885 |
| 蛋白分子量 | 24kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytomembrane |
| 免疫原 | A synthetic peptide of mouse MOG |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein is a key CNS-specific autoantigen for primary demyelination in multiple sclerosis. Although the disease-inducing role of MOG has been established, its precise function in the CNS remains obscure. MOG is a type I integral membrane protein possessing a single extracellular Ig variable domain (Ig-V) (3, 13, 14). The amino acid sequence of MOG is highly conserved among animal species (>90%), indicative of an important biological function. MOG is specifically expressed in the CNS on the outermost lamellae of the myelin sheath as well as the cell body and processes of oligodendrocytes. The developmentally late expression of MOG correlates with the later stages of myelinogenesis, suggesting that MOG has a role in the completion, compaction, and/or maintenance of myelin, further suggesting that MOG has an adhesive function within the CNS . Consistent with MOG's possible adhesive role in the CNS, a homodimeric form of MOG has not only been observed after isolation from the CNS but has additionally been observed in situ. |
| Public Immunogen Range | A synthetic peptide of mouse MOG |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPigRatMouse |
| 应用 | WBIFICCIHC-FIHC-PELISA |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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