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产品简介
英文名称 | Anti-HSPA1A Polyclonal Antibody |
别名 | HEL-S-103;HSP70-1;HSP70-1A;HSP70.1;HSP70I;HSP72;HSPA1 |
宿主 | Rabbit |
稀释比例 | WB 1:2500. |
Gene ID | 3303/3304 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P0DMV8 |
蛋白分子量 | 70kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Cytoskeleton Nucleus |
免疫原 | A synthetic peptide of human HSPA1A |
亚型 | IgG |
性状 | 液体 |
纯化方法 | Affinity purification |
背景资料 | In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Essential for STUB1-mediated ubiquitination and degradation of FOXP3 in regulatory T-cells (Treg) during inflammation. Negatively regulates heat shock-induced HSF1 transcriptional activity during the attenuation and recovery phase period of the heat shock response. |
Public Immunogen Range | 145-195/641aa |
克隆类型 | Polyclonal Antibody |
交叉反应 | Human |
应用 | WB |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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