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产品简介
| 英文名称 | Anti-MAPK3/MAPK1 Polyclonal Antibody |
| 别名 | ERK;ERK-2;MAPK2;p38;p40;p41;p41mapk;p42-MAPK;P42MAPK;PRKM1;PRKM2;ERK1/2 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. |
| Gene ID | 5594/5595 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P27361/P28482 |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 蛋白分子量 | 41/36/38/43kDa |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human MAPK3/MAPK1 |
| 亚型 | IgG |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 背景资料 | Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. About 160 substrates have already been discovered for ERKs. Many of these substrates are localized in the nucleus, and seem to participate in the regulation of transcription upon stimulation. |
| Public Immunogen Range | 1-360aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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