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| 英文名称 | Anti-HSP70 Monoclonal Antibody |
| 别名 | heat shock protein 70 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000-2000. IF 1:100-200. |
| Gene ID | 3303/3304 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P0DMV8/P0DMV9 |
| 蛋白分子量 | 70kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide coupled to KLH |
| 亚型 | IgG1 |
| 性状 | 液体 |
| 纯化方法 | Affinity purification |
| 克隆号 | 3G10 |
| 背景资料 | The 70 kilodalton heat shock proteins (Hsp70s) are a family of ubiquitously expressed heat shock proteins. Proteins with similar structure exist in virtually all living organisms. The Hsp70s are an important part of the cell's machinery for protein folding, and help to protect cells from stress. Hsp70 is usually in an ATP bound state. Hsp70 by itself is characterized by a very weak ATPase activity, such that spontaneous hydrolysis will not occur for many minutes. As newly synthesized proteins emerge from the ribosomes, the substrate binding domain of Hsp70 recognizes sequences of hydrophobic amino acid residues, and interacts with them. This spontaneous interaction is reversible, and in the ATP bound state Hsp70 may relatively freely bind and release peptides. However, the presence of a peptide in the binding domain stimulates the ATPase activity of Hsp70, increasing its normally slow rate of ATP hydrolysis. |
| Public Immunogen Range | A synthetic peptide coupled to KLH |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanPigRatMouse |
| 应用 | WBIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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