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产品简介
| 英文名称 | Anti-GJB6 Polyclonal Antibody |
| 别名 | ED2, EDH, HED, CX30, DFNA3, DFNA3B, DFNB1B |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-5000.IHC 1:50-150. |
| Gene ID | 10804 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O95452 |
| 蛋白分子量 | 30 kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of human GJB6 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Gap junctions allow the transport of ions and metabolites between the cytoplasm of adjacent cells. They are formed by two hemichannels, made up of six connexin proteins assembled in groups. Each connexin protein has four transmembrane segments, two extracellular loops, a cytoplasmic loop formed between the two inner transmembrane segments, and the N- and C-terminus both being in the cytoplasm. The specificity of the gap junction is determined by which connexin proteins comprise the hemichannel. In the past, connexin protein names were based on their molecular weight, however the new nomenclature uses sequential numbers based on which form (alpha or beta) of the gap junction is present. This gene encodes one of the connexin proteins. Mutations in this gene have been found in some forms of deafness and in some families with hidrotic ectodermal dysplasia. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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