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产品简介
| 英文名称 | Anti-ANO1 Polyclonal Antibody |
| 别名 | DOG1;TAOS2;ORAOV2;TMEM16A |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:200-1000. |
| Gene ID | 55107 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q5XXA6 |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 蛋白分子量 | 94/98/114kDa |
| 亚细胞定位 | Cytoplasm Cell membrane |
| 免疫原 | A synthetic peptide of human ANO1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | TMEM16A, also known as DOG1, ORAOV2, TAOS2 or ANO1 (anoctamin 1), is a 986 amino acid multi-pass membrane protein that localizes to both the cell membrane and the cytoplasm and belongs to the anoctamin family. Expressed in a variety of tissues with highest expression in skeletal muscle and liver, TMEM16A functions as a calcium-activated chloride channel that is required for normal tracheal development. Human TMEM16A shares 90% sequence identity with its mouse counterpart, suggesting a conserved role between species. TMEM16A is present in breast, pancreatic, gastric, and uterine cancers, as well as in neck, ovarian and parathyroid tumors, suggesting a role for TMEM16A in carcinogenesis. Three isoforms of TMEM16A exist due to alternative splicing events. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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