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产品简介
| 英文名称 | Anti-CDK14 Polyclonal Antibody |
| 别名 | PFTK1;PFTAIRE1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:200-1000.IHC 1:25-100. |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O94921 |
| 蛋白分子量 | 53 kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of human CDK14 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Serine/threonine-protein kinase involved in the control of the eukaryotic cell cycle, whose activity is controlled by an associated cyclin. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by mediating the phosphorylation of LRP6 at 'Ser-1490', leading to the activation of the Wnt signaling pathway. Acts as a regulator of cell cycle progression and cell proliferation via its interaction with CCDN3. Phosphorylates RB1 in vitro, however the relevance of such result remains to be confirmed in vivo. May also play a role in meiosis, neuron differentiation and may indirectly act as a negative regulator of insulin-responsive glucose transport. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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