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产品简介
| 英文名称 | Anti-RUNX1T1 Polyclonal Antibody |
| 别名 | AML1-MTG8; AML1T1; CBFA2T1; CDR; ETO; MTG8; ZMYND2; protein CBFA2T1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:8000-12000. |
| Gene ID | 862 |
| Swiss Prot | Q06455 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 蛋白分子量 | 68/64/48/45kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.11. |
| 亚细胞定位 | Nucleus |
| 免疫原 | A synthetic peptide of human RUNX1T1 |
| 亚型 | IgG |
| 纯化方法 | Octanoic acid-ammonium sulfate precipitation |
| 背景资料 | This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The translocation is one of the most frequent karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. The chimeric protein is thought to associate with the nuclear corepressor/histone deacetylase complex to block hematopoietic differentiation. Alternative splicing results in multiple transcript variants. |
| Public Immunogen Range | 5-55/604aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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