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产品简介
| 英文名称 | Anti-ITM2B Polyclonal Antibody |
| 别名 | BRI, BRI2, BRICD2B, E25B, E3-16 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:5000-8000. |
| Gene ID | 9445 |
| Swiss Prot | Q9Y287 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| 蛋白分子量 | 30kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.21. |
| 亚细胞定位 | Cytoplasm?Cell membrane |
| 免疫原 | Recombinant protein of human ITM2B |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease. This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide which inhibits the deposition of beta-amyloid. Mutations which result in extension of the C-terminal end of the encoded protein, thereby increasing the size of the secreted peptide, are associated with two neurogenerative diseases, familial British dementia and familial Danish dementia. |
| Public Immunogen Range | 1-266aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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