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产品简介
| 英文名称 | Anti-IL10 Polyclonal Antibody |
| 别名 | IL10;CSIF;GVHDS;IL-10;IL10A;TGIF;interleukin-10 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:5000-8000. |
| Gene ID | 3586 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P22301 |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 蛋白分子量 | 20kDa |
| 亚细胞定位 | Secreted |
| 免疫原 | Recombinant protein of human IL10 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a cytokine produced primarily by monocytes and to a lesser extent by lymphocytes. This cytokine has pleiotropic effects in immunoregulation and inflammation. It down-regulates the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. This cytokine can block NF-kappa B activity, and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice suggested the function of this cytokine as an essential immunoregulator in the intestinal tract. Mutations in this gene are associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. |
| Public Immunogen Range | 1-178aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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