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产品简介
| 英文名称 | Anti-PIM1 Polyclonal Antibody |
| 别名 | PIM;serine/threonine-protein kinase pim-1 |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:100-300. |
| Gene ID | 5292 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P11309 |
| 蛋白分子量 | 35/45kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus?Cytoplasm?? Cell membrane |
| 免疫原 | A synthetic peptide of human PIM1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810). |
| Public Immunogen Range | 310-360/404aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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