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产品简介
| 英文名称 | Anti-XRCC1 Polyclonal Antibody |
| 别名 | XRCC1; RCC; DNA repair protein XRCC1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000 - 1:2000. IF 1:50 - 1:200. |
| Gene ID | 7515 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P18887 |
| 蛋白分子量 | 69kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus |
| 免疫原 | Recombinant fusion protein containing a sequence corresponding to amino acids 1-320 of human XRCC1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIF |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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