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产品简介
| 英文名称 | Anti-FGFR3 Polyclonal Antibody |
| 别名 | ACH;CD333;CEK2;HSFGFR3EX;JTK4 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-1:2000. IHC 1:50-1:100. |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P22607 |
| 蛋白分子量 | 88kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane Cytoplasmic vesicle Endoplasmic reticulum Secreted Single-pass type I membrane protein |
| 免疫原 | Recombinant protein of human FGFR3 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia. Three alternatively spliced transcript variants that encode different protein isoforms have been described. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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