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产品简介
| 英文名称 | Anti-TCL1A Polyclonal Antibody |
| 别名 | TCL1 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-1:2000. |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P56279 |
| 蛋白分子量 | 13kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Endoplasmic reticulum Microsome Nucleus |
| 免疫原 | Recombinant protein of human TCL1A |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Overexpression of the TCL1 gene in humans has been implicated in the development of mature T cell leukemia, in which chromosomal rearrangements bring the TCL1 gene in close proximity to the T-cell antigen receptor (TCR)-alpha (MIM 186880) or TCR-beta (MIM 186930) regulatory elements (summarized by Virgilio et al., 1998 [PubMed 9520462]). In normal T cells TCL1 is expressed in CD4-/CD8- cells, but not in cells at later stages of differentiation. TCL1 functions as a coactivator of the cell survival kinase AKT (MIM 164730) (Laine et al., 2000 [PubMed 10983986]). |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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