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产品简介
| 英文名称 | Anti-COL1A1 Polyclonal Antibody |
| 别名 | EDSC;OI1;OI2;OI3;OI4 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. IF 1:50-200 |
| Gene ID | 1277 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P02452 |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 蛋白分子量 | 116/139kDa |
| 亚细胞定位 | Secreted extracellular matrix extracellular space |
| 免疫原 | A synthetic peptide of human COL1A1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene encodes the pro-alpha1 chains of type I collagen whose triple helix comprises two alpha1 chains and one alpha2 chain. Type I is a fibril-forming collagen found in most connective tissues and is abundant in bone, cornea, dermis and tendon. Mutations in this gene are associated with osteogenesis imperfecta types I-IV, Ehlers-Danlos syndrome type VIIA, Ehlers-Danlos syndrome Classical type, Caffey Disease and idiopathic osteoporosis. Reciprocal translocations between chromosomes 17 and 22, where this gene and the gene for platelet-derived growth factor beta are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans, resulting from unregulated expression of the growth factor. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | MouseRatHuman |
| 应用 | WBIHCIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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