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产品简介
| 英文名称 | Anti-CEBPA Polyclonal Antibody |
| 别名 | CEBPA; C/EBP-alpha; CEBP; CCAAT/enhancer-binding protein alpha |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-1:2000. IHC 1:-50-1:200. |
| Gene ID | 1050 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P49715 |
| 蛋白分子量 | 25/35/37/41kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus |
| 免疫原 | Recombinant protein of human CEBPA |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This intronless gene encodes a transcription factor that contains a basic leucine zipper (bZIP) domain and recognizes the CCAAT motif in the promoters of target genes. The encoded protein functions in homodimers and also heterodimers with CCAAT/enhancer-binding proteins beta and gamma. Activity of this protein can modulate the expression of genes involved in cell cycle regulation as well as in body weight homeostasis. Mutation of this gene is associated with acute myeloid leukemia. The use of alternative in-frame non-AUG (GUG) and AUG start codons results in protein isoforms with different lengths. Differential translation initiation is mediated by an out-of-frame, upstream open reading frame which is located between the GUG and the first AUG start codons. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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