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产品简介
| 英文名称 | Anti-DDR2 Monoclonal Antibody |
| 别名 | DDR2;Discoidin domain receptor 2;MIG20a;NTRKR3;TKT;TYRO10;Tyrosine protein kinase TYRO10 |
| 宿主 | Mouse |
| 稀释比例 | WB : 1:1000-1:6000. IF 1:50-1:500. ELISA 1:50-1:500. |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q16832 |
| 蛋白分子量 | 97kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane |
| 免疫原 | DDR2 fusion protein |
| 亚型 | IgG1 |
| 纯化方法 | Affinity purification |
| 克隆号 | 1E9A10 |
| 背景资料 | Tyrosine kinase involved in the regulation of tissues remodeling (PubMed:30449416). It functions as cell surface receptor for fibrillar collagen and regulates cell differentiation, remodeling of the extracellular matrix, cell migration and cell proliferation. Required for normal bone development. Regulates osteoblast differentiation and chondrocyte maturation via a signaling pathway that involves MAP kinases and leads to the activation of the transcription factor RUNX2. Regulates remodeling of the extracellular matrix by up-regulation of the collagenases MMP1, MMP2 and MMP13, and thereby facilitates cell migration and tumor cell invasion. Promotes fibroblast migration and proliferation, and thereby contributes to cutaneous wound healing. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | Human |
| 应用 | WBELISAIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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