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产品简介
| 英文名称 | Anti-TNNI3 Polyclonal Antibody |
| 别名 | CMD1FF; CMD2A; CMH7; RCM1; TNNC1; cTnI; troponin I3, cardiac type |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:100-300. IF 1:50-200. |
| Gene ID | 21954 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P48787 |
| 蛋白分子量 | 24kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of human TNNI3 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). |
| Public Immunogen Range | 161-211/211aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIFIHC |
| 规格 | 50ul100ul |
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