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产品简介
| 英文名称 | Anti-HLA-DMA Polyclonal Antibody |
| 别名 | D6S222E; DMA; HLADM; RING6; major histocompatibility complex; class II; DM alpha |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:50-200.IF 1:50-200. |
| Gene ID | 3108 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P28067 |
| 蛋白分子量 | 29kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Cell membrane |
| 免疫原 | A synthetic peptide of human HLA-DMA |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. |
| Public Immunogen Range | 110-160/261aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | IHCIF |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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