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产品简介
| 英文名称 | Anti-TGS1 Polyclonal Antibody |
| 别名 | CLL associated antigen KW 2;HCA137;NCOA6IP;PIMT;PIPMT;TGS1;Trimethylguanosine synthase |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:100-300. |
| Gene ID | 96764 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q96RS0 |
| 蛋白分子量 | 97kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | Recombinant protein of human TGS1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Catalyzes the 2 serial methylation steps for the conversion of the 7-monomethylguanosine caps of snRNAs and snoRNAs to a 2,2,7-trimethylguanosine cap structure. The enzyme is specific for guanine, and N7 methylation must precede N2 methylation. Hypermethylation of the m7G cap of U snRNAs leads to their concentration in nuclear foci, their colocalization with coilin and the formation of canonical Cajal bodies . Plays a role in transcriptional regulation. |
| Public Immunogen Range | 713-853aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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