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产品简介
| 英文名称 | Anti-ECD Polyclonal Antibody |
| 别名 | ECD;GCR2;HSGT1;Protein ecdysoneless homolog;Protein SGT1;SGT1;Suppressor of GCR2 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:25-100. |
| Gene ID | 11319 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O95905 |
| 蛋白分子量 | 68/73/78kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus |
| 免疫原 | Recombinant protein of human ECD |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Regulator of p53/TP53 stability and function. Inhibits MDM2-mediated degradation of p53/TP53 possibly by cooperating in part with TXNIP. May be involved transcriptional regulation. In vitro has intrinsic transactivation activity enhanced by EP300. May be a transcriptional activator required for the expression of glycolytic genes . Involved in regulation of cell cycle progression. Proposed to disrupt Rb-E2F binding leading to transcriptional activation of E2F proteins . The cell cycle -regulating function may depend on its RUVBL1-mediated association with the R2TP complex . May play a role in regulation of pre-mRNA splicing . |
| Public Immunogen Range | 295-644aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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