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产品简介
| 英文名称 | Anti-Artemis (phospho Ser516) Polyclonal Antibody |
| 别名 | SCIDA;SNM1C;A-SCID;RS-SCID;DCLREC1C |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:100-300. |
| Gene ID | 64421 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q96SD1 |
| 蛋白分子量 | 78kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus |
| 免疫原 | A synthetic peptide of human Artemis (phospho Ser516) |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This protein exhibits single-strand specific 5'-3' exonuclease activity in isolation and acquires endonucleolytic activity on 5' and 3' hairpins and overhangs when in a complex with PRKDC. The latter activity is required specifically for the resolution of closed hairpins prior to the formation of the coding joint. May also be required for the repair of complex DSBs induced by ionizing radiation, which require substantial end-processing prior to religation by non homologous end joining. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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