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产品简介
| 英文名称 | Anti-Caspase 3/P17/P19 Monoclonal Antibody |
| 别名 | Apopain;CASP 3;CASP3;Caspase 3;Caspase3;Caspase-3;CPP 32;CPP32;CPP32B;Cysteine protease CPP32;Protein Yama;SCA 1;SREBP cleavage activity 1 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000-3000. IHC 1:150-600. IF 1:50-500. |
| Gene ID | 836 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P42574 |
| 蛋白分子量 | 32kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Caspase 3/p17/p19 fusion protein |
| 亚型 | IgG1 |
| 纯化方法 | Affinity purification |
| 背景资料 | Caspases, a family of endoproteases, are critical players in cell regulatory networks controlling inflammation and cell death. Initiator caspases (caspase-2, -8, -9, -10, -11, and -12) cleave and activate downstream effector caspases (caspase-3, -6, and -7), which in turn execute apoptosis by cleaving targeted cellular proteins. Caspase 3 (also named CPP32, SCA-1, and Apopain) proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at the beginning of apoptosis. Caspase 3 plays a key role in the activation of sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Caspase 3 can also form heterocomplex with other proteins and performs the molecular mass of 50-70 kDa. This antibody can recognize p17, p19 and p32 of Caspase 3. |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBELISAIFIHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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