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产品简介
| 英文名称 | Anti-CDC20 Polyclonal Antibody |
| 别名 | CDC20A;bA276H19.3;p55CDC |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:2000-5000. IHC 1:25-100. |
| Gene ID | 991 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q12834 |
| 蛋白分子量 | 54kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | A synthetic peptide of Human CDC20 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Required for full ubiquitin ligase activity of the anaphase promoting complex/cyclosome (APC/C) and may confer substrate specificity upon the complex. Is regulated by MAD2L1: in metaphase the MAD2L1-CDC20-APC/C ternary complex is inactive and in anaphase the CDC20-APC/C binary complex is active in degrading substrates. The CDC20-APC/C complex positively regulates the formation of synaptic vesicle clustering at active zone to the presynaptic membrane in postmitotic neurons. CDC20-APC/C-induced degradation of NEUROD2 induces presynaptic differentiation. |
| Public Immunogen Range | 65-115/499aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRat |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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