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产品简介
| 英文名称 | Anti-PAK4 Polyclonal Antibody |
| 别名 | PAK4 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-1000. IHC 1:50-100. |
| Gene ID | 10298 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O96013 |
| 蛋白分子量 | 47/48/54/64kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human PAK4 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | PAK proteins, a family of serine/threonine p21-activating kinases, include PAK1, PAK2, PAK3 and PAK4. PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling. They serve as targets for the small GTP binding proteins Cdc42 and Rac and have been implicated in a wide range of biological activities. PAK4 interacts specifically with the GTP-bound form of Cdc42Hs and weakly activates the JNK family of MAP kinases. PAK4 is a mediator of filopodia formation and may play a role in the reorganization of the actin cytoskeleton. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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