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产品简介
| 英文名称 | Anti-CCL5 Polyclonal Antibody |
| 别名 | CCL5;D17S136E;RANTES;SCYA5;SIS-delta;SISd;TCP228;eoCP |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. IHC 1:50-200. |
| Gene ID | 6352 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P13501 |
| 蛋白分子量 | 9kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Secreted |
| 免疫原 | Recombinant protein of human CCL5 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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