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产品简介
英文名称 | Anti-GAPDH Polyclonal Antibody |
别名 | G3PD;GAPD;HEL-S-162eP;GAPDH |
宿主 | Rabbit |
稀释比例 | WB 1:1000-10000. IHC 1:50-100. IF 1:20-50. IP 1:20-50. |
Gene ID | 2597 |
保存 | Store at -20°C. Avoid freeze / thaw cycles. |
Swiss Prot | P04406 |
蛋白分子量 | 31/36kDa |
储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
亚细胞定位 | Cytoplasm Membrane Nucleus Cytoskeleton Cytosol Perinuclear region |
免疫原 | Recombinant protein of human GAPDH |
亚型 | IgG |
纯化方法 | Affinity purification |
背景资料 | This gene encodes a member of the glyceraldehyde-3-phosphate dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The product of this gene catalyzes an important energy-yielding step in carbohydrate metabolism, the reversible oxidative phosphorylation of glyceraldehyde-3-phosphate in the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). The encoded protein has additionally been identified to have uracil DNA glycosylase activity in the nucleus. Also, this protein contains a peptide that has antimicrobial activity against E. coli, P. aeruginosa, and C. albicans. Studies of a similar protein in mouse have assigned a variety of additional functions including nitrosylation of nuclear proteins, the regulation of mRNA stability, and acting as a transferrin receptor on the cell surface of macrophage. Many pseudogenes similar to this locus are present in the human genome. Alternative splicing results in multiple transcript variants. |
克隆类型 | Polyclonal Antibody |
交叉反应 | HumanRatMouse |
应用 | WBIPIFIHC |
规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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