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产品简介
| 英文名称 | Anti-HO-1/HMOX1 Monoclonal Antibody |
| 别名 | bK286B10, heme oxygenase (decycling) 1, Heme oxygenase 1, HMOX1, HO, HO 1, HO1, HO-1, HSP32 |
| 宿主 | Mouse |
| 稀释比例 | WB 1:1000-6000. IHC 1:500-2000. IF 1:50-500. |
| Gene ID | 3162 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P09601 |
| 蛋白分子量 | 33 kDa |
| 储存液 | Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3. |
| 亚细胞定位 | Endoplasmic reticulum Membrane Microsome |
| 免疫原 | HO-1/HMOX1 fusion protein |
| 亚型 | IgG2a |
| 性状 | liquid |
| 纯化方法 | Affinity purification |
| 背景资料 | Heme oxygenase (HMOX1) catalyzes the first and rate-limiting step in the degradation of heme to yield equimolar quantities of biliverdin Ixa, carbon monoxide (CO), and iron. It has 3 isoforms: HO-1 is highly inducible, whereas HO-2 and HO-3 are constitutively expressed (PMID:10194478). Heme oxygenase-1 (HO-1) is expressed in many tissues and vascular smooth muscle cells, and endothelial cells (PMID:15451051) and has been identified as an important endogenous protective factor induced in many cell types by various stimulants, such as hemolysis, infiammatory cytokines,oxidative stress, heat shock, heavy metals, and endotoxin (PMID: 11522663). And the full-length HO-1 is very unstable and susceptible to truncation that generates an inactive, soluble form (28 kDa). |
| 克隆类型 | Monoclonal Antibody |
| 交叉反应 | HumanPigRatMouse |
| 应用 | WBELISAIFIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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