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产品简介
| 英文名称 | Anti-DVL1 Polyclonal Antibody |
| 别名 | Dishevelled 1;Dishevelled;Dishevelled dsh homolog 1;Dishevelled1;DSH homolog 1;Dvl;MGC54245;Segment polarity protein dishevelled homolog DVL 1;Segment polarity protein dishevelled homolog DVL1;DVL1_HUMAN |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500 IHC-F 1:100-500. Flow-Cyt 3ug/Test. IF 1:100-500. |
| Gene ID | 1855 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O14640 |
| 蛋白分子量 | 73/75kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane Cytoplasm |
| 免疫原 | KLH conjugated synthetic peptide derived from human DVL1 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Required for LEF1 activation upon WNT1 and WNT3A signaling. DVL1 and PAK1 form a ternary complex with MUSK which is important for MUSK-dependent regulation of AChR clustering during the formation of the neuromuscular junction (NMJ). |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIFFlow-CytIHC-FIHC-PELISA |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
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