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产品简介
| 英文名称 | Anti-Collagen IV Polyclonal Antibody |
| 别名 | Arresten;Canstatin;COL4A1;HANAC;ICH;POREN1;Collagen Alpha 1(IV) Chain;Collagen IV Alpha 1 Polypeptide;Collagen Of Basement Membrane Alpha 1 Chain |
| 宿主 | Rabbit |
| 稀释比例 | ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. Flow-Cyt 1μg/Test. IF 1:100-500. |
| Gene ID | 1282 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P02463 |
| 蛋白分子量 | 165kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane Secreted Extracellular matrix |
| 免疫原 | KLH conjugated synthetic peptide derived from human Collagen alpha-1(IV) chain |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPigCowHorseRabbitDogRatMouse |
| 应用 | ELISAIFFlow-CytIHC-FIHC-P |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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