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产品简介
| 英文名称 | Anti-HIF 2 alpha Polyclonal Antibody |
| 别名 | EPAS 1;EPAS-1;EPAS1;EPAS1_HUMAN;HIF 1 alpha like factor;HIF 2 alpha;HIF-1-alpha-like factor;HIF-2-alpha;HIF2-alpha;HIF2A |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. Flow-Cyt 1μg/Test. IF 1:100-500. |
| Gene ID | 13819 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P97481 |
| 蛋白分子量 | 96kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | KLH conjugated synthetic peptide derived from mouse HIF 2 Alpha |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Transcription factor involved in the induction of oxygen regulated genes. Binds to core DNA sequence 5'-[AG]CGTG-3' within the hypoxia response element (HRE) of target gene promoters. Regulates the vascular endothelial growth factor (VEGF) expression and seems to be implicated in the development of blood vessels and the tubular system of lung. May also play a role in the formation of the endothelium that gives rise to the blood brain barrier. Potent activator of the Tie-2 tyrosine kinase expression. Activation requires recruitment of transcriptional coactivators such as CREBPB and probably EP300. Interaction with redox regulatory protein APEX seems to activate CTAD. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanCowHorsePigRatMouse |
| 应用 | WBIFFlow-CytIHC-FIHC-PELISA |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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人Toll样受体2（TLR2）ELISA试剂盒说明书
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