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产品简介
| 英文名称 | Anti-SOCS7 Polyclonal Antibody |
| 别名 | NAP 4;NAP 4 Fragment;NAP4;Nck Ash and phospholipase C binding protein;Nck Ash and phospholipase C gamma binding protein;Nck associated protein 4;NCKAP4;SH2 domain containing SOCS box protein;SOCS 7;SOCS4;SOCS6;Suppressor of cytokine signaling 7 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. ICC 1:100-500. IF 1:100-500. |
| Gene ID | 30837 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | O14512 |
| 蛋白分子量 | 63kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane Cytoplasm |
| 免疫原 | KLH conjugated synthetic peptide derived from human SOCS7 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Regulates signaling cascades probably through protein ubiquitination and/or sequestration. Functions in insulin signaling and glucose homeostasis through IRS1 ubiquitination and subsequent proteasomal degradation. Inhibits also prolactin, growth hormone and leptin signaling by preventing STAT3 and STAT5 activation, sequestering them in the cytoplasm and reducing their binding to DNA. May be a substrate recognition component of a SCF-like E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRabbitRatMouse |
| 应用 | WBIFICCIHC-FIHC-PELISA |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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