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产品简介
| 英文名称 | Anti-phospho-IKB alpha (Ser32 + Ser36) Polyclonal Antibody |
| 别名 | IKBA;IKBalpha;MAD 3;MAD3;NF kappa B inhibitor alpha;NFKBI;NFKBIA |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. IF 1:100-500. |
| Gene ID | 4792 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P25963 |
| 蛋白分子量 | 35kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | KLH conjugated Synthesised phosphopeptide derived from human IKB alpha around the phosphorylation site of Ser32/36 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanDogPigCowRabbitSheepChickenRatMouse |
| 应用 | WBIFIHC-FIHC-PELISA |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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