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产品简介
| 英文名称 | Anti-JNK1+JNK2+JNK3 Polyclonal Antibody |
| 别名 | c Jun N terminal kinase 2;c Jun N terminal kinase 3;JNK;JNK1;JNK2;JNK2ALPHA;JNK2BETA;JNK3;MAPK8;MAPK9 |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. Flow-Cyt 1ug/Test. IF 1:100-500. |
| Gene ID | 5599 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q61831 |
| 蛋白分子量 | 42-47kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus Cytoplasm |
| 免疫原 | KLH conjugated synthetic peptide derived from human JNK1/2/3 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | JNK1(MAPK8) is a member of the MAP kinase family. JNK1 is activated by threonine and tyrosine phosphorylation by either of two dual specificity kinases, MAP2K4 and MAP2K7.JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.JNK3 is a neuron-specific form of c-Jun N-terminal kinases. Through its phosphorylation and nuclear localization, this kinase plays regulatory roles in the signaling pathways of neuronal apoptosis.The JNK pathway is critically involved in diabetes and levels are abnormally elevated in obesity. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPigCowDogRatMouse |
| 应用 | WBIFFlow-CytIHC-FIHC-PELISA |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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