暂无数据
产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品简介
| 英文名称 | Anti-MAP1LC3B Polyclonal Antibody |
| 别名 | LC3II;LC-3Ⅱ;ATG8F;Autophagy related protein LC3 B;Autophagy related ubiquitin like modifier LC3 B;Autophagy-related protein LC3 B;Autophagy-related ubiquitin-like modifier LC3 B;LC3B;MAP1 light chain 3 like protein 2;MAP1 light chain 3-like protein 2;MAP1A/1B light chain 3 B;MAP1A/1BLC3;MAP1A/MAP1B LC3 B;MAP1A/MAP1B light chain 3 B |
| 宿主 | Rabbit |
| 稀释比例 | ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. IF 1:100-500. |
| Gene ID | 81631 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9GZQ8 |
| 蛋白分子量 | 15kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Cytoplasmic vesicle Endomembrane system Lipid-anchor autophagosome autophagosome membrane cytoskeleton |
| 免疫原 | KLH conjugated synthetic peptide derived from human MAP1LC3B |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanDogpigCowHorseRabbitChickenRatMouse |
| 应用 | ELISAIFIHC-FIHC-P |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
暂无数据
我要询价
*联系方式：
(可以是QQ、MSN、电子邮箱、电话等，您的联系方式不会被公开)
*内容：
