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产品简介
| 英文名称 | Anti-CD40L/TNFRSF5 Polyclonal Antibody |
| 别名 | Tumor necrosis factor receptor superfamily , member 5;B cell associated molecule CD40;B cell surface antigen CD40;B cell-associated molecule;B-cell surface antigen CD40;Bp50;CD 40;CD40;CD40 antigen (TNF receptor superfamily member 5);CD40 antigen;CD40 molecule;CD40 molecule, TNF receptor superfamily member 5;CD40 protein;CD40 type II isoform |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. Flow-Cyt 1μg/Test. IF 1:100-500. |
| Gene ID | 958 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P25942 |
| 蛋白分子量 | 31kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane Secreted |
| 免疫原 | KLH conjugated synthetic peptide derived from human CD40/TNFRSF5 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions. Adaptor protein TNFR2 interacts with this receptor and serves as a mediator of the signal transduction. The interaction of this receptor and its ligand is found to be necessary for amyloid-beta-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul2008]. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanDogpigCowRabbitChickenRatMouse |
| 应用 | WBIFFlow-CytIHC-FIHC-PELISA |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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