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产品简介
| 英文名称 | Anti-phospho-PKM(Tyr105) Polyclonal Antibody |
| 别名 | PKM2 (Phospho Tyr105);PKM2 (Phospho Y105);PK 1;PK 2;PK 3;PK Muscle type;PK1;PK2;Pk3;PKL;PKLR;PKM 2;PKM;PKM2;PYKM;Pyruvate kinase 1;Pyruvate kinase 2/3;Pyruvate kinase 3;Pyruvate kinase isozyme R/L;Pyruvate kinase isozymes M1/M2 |
| 宿主 | Rabbit |
| 稀释比例 | ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. IF 1:100-500. |
| Gene ID | 5315 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P14618 |
| 蛋白分子量 | 58kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | KLH conjugated Synthesised phosphopeptide derived from human PKM2 around the phosphorylation site of Tyr105 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Glycolytic enzyme that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate (PEP) to ADP, generating ATP. Stimulates POU5F1-mediated transcriptional activation. Plays a general role in caspase independent cell death of tumor cells. The ratio betwween the highly active tetrameric form and nearly inactive dimeric form determines whether glucose carbons are channeled to biosynthetic processes or used for glycolytic ATP production. The transition between the 2 forms contributes to the control of glycolysis and is important for tumor cell proliferation and survival. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanpigCowHorseRabbitGuineapigDogRatMouse |
| 应用 | ELISAIFIHC-FIHC-P |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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