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产品简介
| 英文名称 | Anti-phospho-STAT3(Ser727) Polyclonal Antibody |
| 别名 | STAT3 (phospho S727);p-STAT3 (phospho S727);STAT3(Phospho Ser727);STAT3(Phospho S727);p-STAT3(Ser727);Acute Phase Response Factor;APRF;DNA binding protein APRF |
| 宿主 | Rabbit |
| 预测交叉反应 | Mouse;Chicken;Dog;pig;Cow;Rabbit;Sheep;Guinea pig |
| 稀释比例 | ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. Flow-Cyt 0.2μg /Test. IF 1:100-500. |
| Gene ID | 6774 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P40763 |
| 蛋白分子量 | 83/88kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | KLH conjugated Synthesised phosphopeptide derived from human STAT3 around the phosphorylation site of Ser727 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Signal transducer and transcription activator that mediates cellular responses to interleukins, KITLG/SCF and other growth factors. May mediate cellular responses to activated FGFR1, FGFR2, FGFR3 and FGFR4. Binds to the interleukin-6 (IL-6)-responsive elements identified in the promoters of various acute-phase protein genes. Activated by IL31 through IL31RA. Cytoplasmic STAT3 represses macroautophagy by inhibiting EIF2AK2/PKR activity. Plays an important role in host defense in methicillin-resistant S.aureus lung infection by regulating the expression of the antimicrobial lectin REG3G (By similarity). |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRat |
| 应用 | ELISAIFIHC-FIHC-PFlow-Cyt |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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