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产品简介
| 英文名称 | Anti-FTO Polyclonal Antibody |
| 别名 | Alpha-ketoglutarate-dependent dioxygenase FTO;Fat mass and obesity-associated protein;Fto;FTO_HUMAN;Protein fatso |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. IF 1:100-500. |
| Gene ID | 79068 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9C0B1 |
| 蛋白分子量 | 58kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | KLH conjugated synthetic peptide derived from human FTO |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPigCowHorseRabbitSheepDogRatMouse |
| 应用 | WBIFIHC-FIHC-PELISA |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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