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产品简介
| 英文名称 | Anti-RNLS Polyclonal Antibody |
| 别名 | C10orf59;Chromosome 10 open reading frame 59;FLJ11218;Hypothetical protein LOC55328;MAO C;Monoamine oxidase C;RENALASE;Renalase, FAD dependent amine oxidase;RNLS antibody;RNLS_HUMAN |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. ELISA 1:500-1000. IHC-P 1:100-500. IHC-F 1:100-500. IF 1:100-500. |
| Gene ID | 55328 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q5VYX0 |
| 蛋白分子量 | 35/38kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Secreted |
| 免疫原 | KLH conjugated synthetic peptide derived from human RNLS |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Probable FAD-dependent amine oxidase secreted by the kidney, which circulates in blood and modulates cardiac function and systemic blood pressure. Degrades catecholamines such as dopamine, norepinephrine and epinephrine in vitro. Lowers blood pressure in vivo by decreasing cardiac contractility and heart rate and preventing a compensatory increase in peripheral vascular tone, suggesting a causal link to the increased plasma catecholamine and heightened cardiovascular risk. High concentrations of catecholamines activate plasma renalase and promotes its secretion and synthesis (By similarity). According to PubMed:17385068, is unlikely that renalase has physiologically relevant catecholamine-oxidizing activity. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanPigHorseRabbitDogRatMouse |
| 应用 | WBIFIHC-FIHC-PELISA |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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