暂无数据
产品名称
起订量
单价(含增值税)
库存(PCS)
起订数量
产品简介
| 英文名称 | Anti-HIV1 gp120 Polyclonal Antibody |
| 别名 | HIV-1 ENV (gp120);HIV1 gp120;HIV1gp120;HIV-1 gp120;Envelope surface glycoprotein gp120;Glycoprotein 120;gp120;gp120 glycoprotein;Human Immunodeficiency Virus 1;SU;Surface protein |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:500-2000. ELISA 1:500-1000. IHC-F 1:100-500. IF 1:100-500. |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P05877 |
| 蛋白分子量 | 53/91kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cell membrane |
| 免疫原 | KLH conjugated synthetic peptide derived from HIV1 Surface protein gp120 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The surface protein gp120 (SU) attaches the virus to the host lymphoid cell by binding to the primary receptor CD4. This interaction induces a structural rearrangement creating a high affinity binding site for a chemokine coreceptor like CXCR4 and/or CCR5. This peculiar 2 stage receptor-interaction strategy allows gp120 to maintain the highly conserved coreceptor-binding site in a cryptic conformation, protected from neutralizing antibodies. Since CD4 also displays a binding site for the disulfide-isomerase P4HB/PDI, a P4HB/PDI-CD4-CXCR4-gp120 complex may form. In that complex, P4HB/PDI could reach and reduce gp120 disulfide bonds, causing major conformational changes in gp120. TXN, another PDI family member could also be involved in disulfide rearrangements in Env during fusion. These changes are transmitted to the transmembrane protein gp41 and are thought to activate its fusogenic potential by unmasking its fusion peptide. |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HIV-1 M:B_MN |
| 应用 | WBIFIHC-FELISA |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
暂无数据
我要询价
*联系方式：
(可以是QQ、MSN、电子邮箱、电话等，您的联系方式不会被公开)
*内容：
