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产品简介
| 英文名称 | Anti-TDG Polyclonal Antibody |
| 别名 | C JUN leucine zipper interactive protein;C JUN leucine zipper interactive protein;C-JUN leucine zipper interactive protein JZA-3;E130317C12Rik;EC 3.2.2.29;G/T mismatch specific thymine DNA glycosylase;G/T mismatch specific thymine DNA glycosylase;G/T mismatch-specific thymine DNA glycosylase;JZA 3;Jza1;T:G mismatch thymine glycosylase;Tdg;TDG_HUMAN;Thymine DNA glycosylase;Thymine-DNA glycosylase; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. |
| Gene ID | 6996 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q13569 |
| 蛋白分子量 | 46kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Nucleus |
| 免疫原 | A synthetic peptide of Human TDG |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene belongs to the TDG/mug DNA glycosylase family. Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine. With lower activity, this enzyme also removes thymine from C/T and T/T mispairings. TDG can also remove uracil and 5-bromouracil from mispairings with guanine. This enzyme plays a central role in cellular defense against genetic mutation caused by the spontaneous deamination of 5-methylcytosine and cytosine. This gene may have a pseudogene in the p arm of chromosome 12. |
| Public Immunogen Range | 225-275/410aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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