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产品简介
| 英文名称 | Anti-HTR6 Polyclonal Antibody |
| 别名 | 5 HT 6;5 HT6;5 HT6R;5 hydroxytryptamine (serotonin) receptor 6 G protein coupled;5 hydroxytryptamine 6 receptor;5 hydroxytryptamine receptor 6;5-HT-6;5-HT6;5-hydroxytryptamine receptor 6;5HT 6;5HT6R_HUMAN;HTR 6;Htr6;Serotonin receptor 6; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| Gene ID | 3362 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P50406 |
| 蛋白分子量 | 47kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of Human HTR6 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | 5-HT6, a Serotonin Receptor, appears to regulate cholinergic neurotransmission in the brain rather than the expected interaction as a modulator of dopaminergic transmission. This interaction predicts a possible role for 5-HT6 Receptor antagonists in the treatment of learning and memory disorders. The 5-HT6 Receptor is abundant in limbic areas, which participate in the control of mood and emotion. Some antidepressants and antipsychotics are potent 5-HT6 Receptor antagonists, making this gene valuable for the pharmaceutical industry. 5-HT6 may be involved in the pathogenesis of mood disorders, schizophrenia, in Alzheimer's disease. A splice variant that has a 289bp deletion in the transmembrane region IV and the third intracellular loop has been isolated. 5-HT6 Receptor has been reported primarily in striatum of the brain. Expression has also been seen in stomach, spinal cord, and the lymphoid tissues of rats, including peripheral blood lymphocytes, spleen, and thymus. ESTs have been isolated from brain libraries. |
| Public Immunogen Range | 235-285/440aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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