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产品简介
| 英文名称 | Anti-APOBEC3D/F Polyclonal Antibody |
| 别名 | A3D;ABC3D_HUMAN;APOBEC3D;APOBEC3DE;APOBEC3E;Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3D;Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3E pseudogene;ARP6;bK150C2.9;BK150C2.9 protein;DNA dC >dU editing enzyme APOBEC 3D;DNA dC->dU-editing enzyme APOBEC-3D;hCG_41704;HCG41704, isoform CRA_b;Probable DNA dC->dU-editing enzyme APOBEC-3D;Apolipoprotein B mRNA editing enzyme, catalytic polypeptide like 3F;ARP8;DNA dC->dU-editing enzyme APOBEC-3F;Induced upon T cell activation;KA6; |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:50-200. |
| Gene ID | 140564/200316 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q96AK3/Q8IUX4 |
| 蛋白分子量 | 9/12/45/47kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of Human APOBEC3D/F |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | DNA deaminase (cytidine deaminase) which acts as an inhibitor of retrovirus replication and retrotransposon mobility via deaminase-dependent and -independent mechanisms. Exhibits antiviral activity against vif-deficient HIV-1. After the penetration of retroviral nucleocapsids into target cells of infection and the initiation of reverse transcription, it can induce the conversion of cytosine to uracil in the minus-sense single-strand viral DNA, leading to G-to-A hypermutations in the subsequent plus-strand viral DNA. The resultant detrimental levels of mutations in the proviral genome, along with a deamination-independent mechanism that works prior to the proviral integration, together exert efficient antiretroviral effects in infected target cells. Selectively targets single-stranded DNA and does not deaminate double-stranded DNA or single-or double-stranded RNA. May inhibit the mobility of LTR and non-LTR retrotransposons. |
| Public Immunogen Range | 220-270/386aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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