Anti-ALPP/ALPG/ALPI Polyclonal Antibody-上海极威生物商城-Elisa试剂盒,白介素ELISA试剂盒,酶联免疫试剂盒,Gibco胎牛血清,Hyclone胎牛血清,胎牛血清等实验耗材一站式采购平台

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产品简介

英文名称	Anti-ALPP/ALPG/ALPI Polyclonal Antibody
别名	Alkaline phosphatase;Alkaline phosphatase placental;Alkaline phosphatase placental type;Alkaline phosphatase Regan isozyme;ALP;Alp1;ALPP;FLJ61142;Germ-cell alkaline phosphatase;nagao isozyme;OTTHUMP00000164354;PALP;Placental alkaline phosphatase 1;placental heat-stable alkaline phosphatase;placental type;PLAP;PLAP-1;PLAP1;PPB1_HUMAN;Akp5;Alkaline phosphatase;Alkaline phosphatase Nagao isozyme;Alkaline phosphatase placental like;ALP 1;ALP-1;ALP1;ALPG;ALPPL 2;ALPPL;ALPPL2;C77216;D1Ertd816e;GCAP;Germ cell alkaline phosphatase;Nagao isozyme;Placental alkaline phosphatase-like;Placental like alkaline phosphatase;placental-like;PLAP like;PLAP-like;PPBN_HUMAN;Testicular and thymus alkaline phosphatase;Alkaline Phosphatase/ALPP/ALPI
宿主	Rabbit
稀释比例	WB 1:2000-5000. IHC 1:50-200.
Gene ID	250/251/248
保存	Store at -20°C. Avoid freeze / thaw cycles.
Swiss Prot	P05187/P10696/P09923
蛋白分子量	57/58kDa
储存液	Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.
亚细胞定位	Cytoplasm
免疫原	A synthetic peptide of Human ALPP/ALPG/ALPI
亚型	IgG
纯化方法	Affinity purification
背景资料	ALPP (Alkaline phosphatase placental type; also SEAP, PALP-1 and ALP) is a 66-68 kDa glycoprotein member of the alkaline phosphatase family of molecules. It is principally expressed by 2nd and 3rd trimester synctiotrophoblasts and tumor cells, and represents one of four alkaline phosphatase isozymes. Experimentally, it cleaves phosphate monoesters into alcohol and phosphate. Human ALPP is synthesized as a 535 amino acid (aa) preproprecursor. It contains a 22 aa signal sequence, a 484 mature region (aa 23-506), and a 29 aa C-terminal propeptide that is cleaved to generate a GPI linkage at Asp506. The ALPP gene is highly allelic and may generate three potential splice variants that involve the signal sequence. The ALPP enzyme utilizes one Mg and two Zn ions, and functions as either a homodimer, or a heterodimer with the related Intestinal (ALPI) and Germ cell (GCAP) family members on the cell surface. ALPP is reported to oligomerize under certain conditions. Over aa 23-506, human ALPP shares 96% and 77% aa identity with chimpazeee ALPP and mouse embryonic-type alkaline phosphatase, respectively. It also shares 88% and 98% aa identity with IAP and GCAP, respectively. Over aa 23-506, human ALPP shares 86% aa identity with human ALPI.
Public Immunogen Range	200-250/532aa
克隆类型	Polyclonal Antibody
交叉反应	HumanMouse
应用	WBIHC
规格	50ul100ul