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产品简介
| 英文名称 | Anti-MSN Polyclonal Antibody |
| 别名 | Epididymis luminal protein 70;HEL70;Membrane organizing extension spike protein;Membrane-organizing extension spike protein;MOES_HUMAN;Moesin;Moesin/anaplastic lymphoma kinase fusion protein;Msn;MSN/ALK fusion;CB567;CG12537;DFNB24;ESP10;Hh-induced MATH and BTB domain-containing protein;HIB;Moesin-B;Protein roadkill;RADI_HUMAN;Radixin;RDX;Villin 2 ezrin;CVIL;CVL;Cytovillin 2;Cytovillin;DKFZp762H157;Epididymis secretory protein Li 105;EZR;EZRI_HUMAN;Ezrin;FLJ26216;HEL S 105;MGC1584;p81;VIL 2;VIL2;Villin 2 (ezrin);Villin 2;Villin-2;Villin2; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:8000-12000. IHC 1:100-300. IF 1:50-200. |
| Gene ID | 4478 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P26038 |
| 蛋白分子量 | 68kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of human MSN |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Ezrin-radixin-moesin (ERM) family protein that connects the actin cytoskeleton to the plasma membrane and thereby regulates the structure and function of specific domains of the cell cortex. Tethers actin filaments by oscillating between a resting and an activated state providing transient interactions between moesin and the actin cytoskeleton. Once phosphorylated on its C-terminal threonine, moesin is activated leading to interaction with F-actin and cytoskeletal rearrangement. These rearrangements regulate many cellular processes, including cell shape determination, membrane transport, and signal transduction. The role of moesin is particularly important in immunity acting on both T and B-cells homeostasis and self-tolerance, regulating lymphocyte egress from lymphoid organs. Modulates phagolysosomal biogenesis in macrophages (By similarity). Participates also in immunologic synapse formation. |
| Public Immunogen Range | 455-505/577aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanCowRatMouse |
| 应用 | WBIFIHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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