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产品简介
| 英文名称 | Anti-RABEPK/P40 Polyclonal Antibody |
| 别名 | 40 kDa Rab9 effector protein;p40;RAB9P40;RABEPK |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:2000-6000. IP 0.5-4.0 ug for IP and 1:500-2000 for WB. IHC 1:50-500. IF 1:50-500. |
| Gene ID | 10244 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q7Z6M1 |
| 蛋白分子量 | 35/41kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Endosome Membrane |
| 免疫原 | Antigen affinity purification |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Rab9 GTPase is required for the transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network in living cells, and in an in vitro system that reconstitutes this process. P40 is an effector of Rab9 that interacts preferentially with the active form of Rab9. p40 does not interact with Rab7 or K-Ras; it also fails to bind Rab9 when it is bound to GDI. The protein is found in cytosol, yet a significant fraction (~30%) is associated with cellular membranes. P40 is a very potent transport factor in that the pure, recombinant protein can stimulate, significantly, an in vitro transport assay that measures transport of mannose 6-phosphate receptors from endosomes to the trans-Golgi network. |
| 克隆类型 | Polyclonal Antibody |
| 应用 | WBELISAIFIHCIP |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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