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产品简介
| 英文名称 | Anti-CYP2C19 Polyclonal Antibody |
| 别名 | Cytochrome P450 2C19;CYPIIC17;CYPIIC19;Cytochrome P450-11A;Cytochrome P450-254C;Mephenytoin 4-hydroxylase;(S)-limonene 7-monooxygenase;(S)-limonene 6-monooxygenase;(R)-limonene 6-monooxygenase |
| 宿主 | Rabbit |
| 稀释比例 | IHC 1:100-300. |
| Gene ID | 1557 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | P33261 |
| 蛋白分子量 | 56kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | A synthetic peptide of human CYP2C19 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | A cytochrome P450 monooxygenase involved in the metabolism of polyunsaturated fatty acids (PUFA) . Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates PUFA specifically at the omega-1 position. Catalyzes the epoxidation of double bonds of PUFA . Also metabolizes plant monoterpenes such as limonene. Oxygenates (R)- and (S)-limonene to produce carveol and perillyl alcohol. Responsible for the metabolism of a number of therapeutic agents such as the anticonvulsant drug S-mephenytoin, omeprazole, proguanil, certain barbiturates, diazepam, propranolol, citalopram and imipramine. Hydroxylates fenbendazole at the 4' position. |
| Public Immunogen Range | 380-430/490aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | Human |
| 应用 | IHC |
| 规格 | 50ul100ul |
注意：
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗，食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康，请穿好实验服并佩戴一次性手套和口罩操作。
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