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产品简介
| 英文名称 | Anti-USP18 Polyclonal Antibody |
| 别名 | 43 kDa ISG15 specific protease;43 kDa ISG15-specific protease;EC 3.1.2.;hUBP43;Interferon Stimulated Gene 43 kD;ISG15 Specific Processing Protease;ISG15-specific-processing protease;ISG43;Ubiquitin Specific Peptidase 18;Ubiquitin Specific Protease 18 43 kD;Ubiquitin Specific Protease 18;Ubl carboxyl terminal hydrolase 18;Ubl carboxyl-terminal hydrolase 18;Ubl thioesterase 18;Ubl thiolesterase 18;Ubp15;UBP18_HUMAN;USP18; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. |
| Gene ID | 11274 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q9UMW8 |
| 蛋白分子量 | 41/43kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm Nucleus |
| 免疫原 | Recombinant protein of human USP18 |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | The protein encoded by this gene belongs to the ubiquitin-specific proteases (UBP) family of enzymes that cleave ubiquitin from ubiquitinated protein substrates. It is highly expressed in liver and thymus, and is localized to the nucleus. This protein efficiently cleaves only ISG15 (a ubiquitin-like protein) fusions, and deletion of this gene in mice results in a massive increase of ISG15 conjugates in tissues, indicating that this protein is a major ISG15-specific protease. Mice lacking this gene are also hypersensitive to interferon, suggesting a function of this protein in downregulating interferon responses, independent of its isopeptidase activity towards ISG15. |
| Public Immunogen Range | 1-372aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WB |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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