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| 英文名称 | Anti-EIF3I Polyclonal Antibody |
| 别名 | eIF-3-beta;eIF3 beta;eIF3 p36;eIF3-beta;eIF3-p36;eIF3i;EIF3I_HUMAN;EIF3S2;EIF3S2;formerly;Eukaryotic translation initiation factor 3 subunit 2;Eukaryotic translation initiation factor 3 subunit 2 beta;Eukaryotic translation initiation factor 3 subunit I;eukaryotic translation initiation factor 3;subunit 2 (beta;36kD;eukaryotic translation initiation factor 3;subunit 2 beta;36kDa;eukaryotic translation initiation factor 3;subunit 2;formerly;eukaryotic translation initiation factor 3;subunit I;Predicted protein of HQ2242;PRO2242;TGF beta receptor interacting protein 1;TGF-beta receptor-interacting protein 1;TGFbeta receptor interacting protein 1;TGFbeta receptor-interacting protein 1;TRIP 1;TRIP-1;TRIP1; |
| 宿主 | Rabbit |
| 稀释比例 | WB 1:1000-3000. IHC 1:50-200. |
| Gene ID | 8668 |
| 保存 | Store at -20°C. Avoid freeze / thaw cycles. |
| Swiss Prot | Q13347 |
| 蛋白分子量 | 37kDa |
| 储存液 | Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3. |
| 亚细胞定位 | Cytoplasm |
| 免疫原 | Recombinant protein of human EIF3I |
| 亚型 | IgG |
| 纯化方法 | Affinity purification |
| 背景资料 | Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). |
| Public Immunogen Range | 1-326aa |
| 克隆类型 | Polyclonal Antibody |
| 交叉反应 | HumanRatMouse |
| 应用 | WBIHC |
| 规格 | 50ul100ul |
注意:
1.本产品仅供科研使用。请勿用于医药、临床诊断或治疗,食品及化妆品等用途。请勿存放于普通住宅区。
2.为了您的安全和健康,请穿好实验服并佩戴一次性手套和口罩操作。
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